You can try this way in V3 of the simplecartjs script,
if(simpleCart.items().length == 0)
{
//No items in the cart
}
If you want to check a particular item already present in the cart, using jQuery.simpleCart.bind('beforeAdd', function (item) {
if (simpleCart.has(item))
{
alert("Already in the Cart");
return false;
}
});